The U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) gives aid disproportionately to countries with epidemics generalized across risk groups compared with those with epidemics concentrated among men who have sex with men (MSM) or injection drug users (IDUs). Investigators analyzed recent funding for 19 nations and four regions representing 67 percent of all PEPFAR funding from 2010 to 2014. In 2014, nations with generalized epidemics received 1.5 times more funding per person living with HIV than countries with epidemics concentrated among MSM or IDUs and 6.3 times more funding than nations with epidemics primarily concentrated among MSM, IDUs and heterosexuals in which the HIV prevalence among MSM and IDUs is more than 10 times that of the general population.